Prof. Dr. TÜLAY KÖKEN(UYG.VE ARŞ.HAS.)
E-posta Adresi tkoken@aku.edu.tr
Uzmanlık Alanı : BİYOKİMYA VE KLİNİK BİYOKİMYA
Yabancı Dili : İNGİLİZCE
Lisans : --
Yüksek Lisans : İSTANBUL ÜNİ.CERRAHPAŞA TIP FAK. 1990
Doktora : OSMANGAZİ ÜNİ.TIP FAK. BİYOKİMYA VE KLİNİK BİYOKİM 1997
Doçentlik : AFYON KOCATEPE ÜNİVERSİTESİ 2004
Profesörlük : AFYON KOCATEPE ÜNİVERSİTESİ 2010


 
Akademik ve İdari Görevleri


Yayınları : 
0SCI,SSCI,AHCI Tarafından Taranan Dergide Yayınlanan Makaleler
1Erythropoietin improves oxidative stress following spinal cord trauma in rats, Injury, 39(12), 1408-13, 2008(Yazıhan N, Uzuner K, Salman B, Vural M, Arslantaş A., ile birlikte)
2Effects of carvacrol on defects of ischemia-reperfusion in the rat liver, Phytomedicine, 15(6-7), 447-52, 2008(Canbek M, Uyanoglu M, Bayramoglu G, Senturk H, Erkasap N, Uslu S, Demirustu C, Aral E, Husnu Can Baser K., ile birlikte)
3Increased serum osteoprotegerin levels associated with decreased bone mineral density in familial Mediterranean fever., Tohoku J Exp Med, 217(4), 321-7, 2009(Yuksel S, Samli H, Colbay M, Dundar U, Acarturk G, Demir S, Aktepe OC, Kavuncu V, Solak M., ile birlikte)
4Protective effects of doxycycline in ischemia/reperfusion injury on kidney. , J Physiol Biochem., 65(2), 183-91., 2009(Kucuk A, Kabadere S, Tosun M, Kinaci MK, Isikli B, Erkasap N., ile birlikte)
5Effects of Doxycycline on Renal Ischemia Reperfusion Injury Induced by Abdominal Compartment Syndrome.J Surg Res. 2009 Oct 22. , JOURNAL OF SURGICAL RESEARCH , 167 (1) , 113-120 , 2011(Ihtiyar E, Fatih Yaşar N, Erkasap N, Tosun M, Oner S, Erkasap S, ile birlikte)
6A.Long-term alcohol consumption increases pro-matrix metalloproteinase-9 levels via oxidative stress. , J Med Toxicol., 6(2), 126-30., 2010(Gursoy F, Kahraman , ile birlikte)
7Prevention of ovarian hyperstimulation syndrome in a rat model: efficacy comparison between cabergoline and meloxicam. , Acta Obstet Gynecol Scand. , 89(5), 692-9, 2010(Saylan A, Arioz DT, Dilek H, Saylan F, Yilmazer M., ile birlikte)
8Effects of hemodialysis period on levels of blood trace elements and oxidative stress. , Clin Exp Nephrol. , 14(5), 463-8, 2010(Koca T, Berber A, Koca HB, Demir TA, , ile birlikte)
9Changes in Serum Asymmetric Dimethylarginine and Endothelial Markers Levels With Varying Periods of Hemodialysis., THERAPEUTIC APHERESIS AND DIALYSIS , 18(4), 361-367, 2014(Yaman A, Karabag F, Demir S, , ile birlikte)
10 Can platelet indices predict obstruction level of pulmonary vascular bed in patients with acute pulmonary embolism? , CLINICAL RESPIRATORY JOURNAL , 8(1), 33-40, 2014(Gunay E, Ulasli SS, Kacar E, Halici B, Unlu E, Tunay K, Ozkececi G, Unlu M., ile birlikte)
11Lowered serum total L-carnitine levels are associated with obesity at term pregnancy. , JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE , 26(15), 1479-1483, 2013(Tipi-Akbas P, Arioz DT, Kanat-Pektas M, Koken G, Yilmazer M., ile birlikte)
12Evalution of Serum Lipid Profiles in Turkish Children Aged Two to Eighteen Years., West Indian Med J, 63(6), 588-595, 2014(Toprak D, Bukulmez A, Dogan N, Oztekin O, , ile birlikte)
13L-Carnitine: a new insight into the pathogenesis of endometrial cancer., Arch Gynecol Obstet., 291(5), 1147-52, 2015(Arioz DT, Kanat-Pektas M, Tuncer N, Unlu BS, Koken G, Yilmazer M., ile birlikte)
0SCI, SSCI ve AHCI Dışında Taranan Dergilerde Yayınlanan Makaleler
1Effects of proadrenomedullin N-terminal 20 peptide and calcitonin on isolated perfused rat hearts., Anadolu Kardiyol Derg. , 9(3), 176-82, 2009(9. Kaygisiz, Z., H. Ozden, N. Erkasap, T. Gündüz, M. Ikizler, T. Kural. , ile birlikte)
0Hakemli Dergilerde Yayınlanan Makaleler
1Kronik Böbrek Yetmezliğinde Oksidatif Stres ve Biyomarkırları, Klinik Aktüel Tıp Nefroloji Forumu, 2(1), 14-21, 2008
0Uluslararası Konferans ve Sempozyumlardaki Tebliğler :
1Relation of birth weight with umblical cord growth hormone, insulin like growth factors, ghrelin, and leptin levels in term and preterm neonates, 1st UENPS Congress Global Neonatology and Perinata, Kasım 2008, 125, 2008(Koken R, Bukulmez A, Melek H, Koken G, Guraksin O, Koca B., ile birlikte)
2Comparison of 3 different immunoassay methods for intact parathyroid hormone in hemodialysis patient, World Congress of Nephrology, 22-26 Mayıs 2009, , 2009(Ates F, Demir S, Kahraman A., ile birlikte)
3Prevalence of cobalamin deficiency in Afyonkarahisar elderly population, The First International Symposium on Quality&Accre, 15-18 Nisan 2008, 344, 2009(Toprak D, Dogan N., ile birlikte)
4Effect of IL 28 b polimorphisms on the natural course of HBV infection., İstanbul Türkiye , 24th Annual Conference of APASL, 2015, ., 2015(Demirturk N, Aykin N, Cevik F, Koca B, Dogan N, ile birlikte)
5Apoptotic and Anti-Angiogenic Effects of Apium Graveolens Whole Plant Extract on Prostat Cancer Cell Line, 22. International Congres of Clinical Chemistry an, 2014, ., 2014(Koca HB, Özkurt M, Erkasap N., ile birlikte)
6Antioxidant Properties of Ethanolic Extract of Acorus Calamus on LNCaP Human Prostate Carcinome Cell Line, 22. International Congres of Clinical Chemistry a, 2014, ., 2014(Koca HB, Kuş G, Kabadere S,, ile birlikte)
0Ulusal Konferans ve Sempozyumlardaki Tebliğler :
1Kan sodyum ve potasyum ölçümünde kan gazı cihazı ile biyokimya otoanalizörü sonuçlarının karşılaştırılması, IX. Ulusal Klinik Biyokimya Kongresi, 23-26 Nisan 2009, , 2009(Hünkerler Z, Doğan N, Koca B, Kahraman A., ile birlikte)
2Hepatit B ve Hepatit C’li hemodiyaliz hastalarında adenozin deaminaz düzeyleri, IX. Ulusal Klinik Biyokimya Kongresi, 23-26 Nisan 2009, , 2009(Yaman A, Geçici N, Koca B, Kahraman A., ile birlikte)
3Homosisteinin indüklediği oksidatif stres üzerinde siyah üzüm suyunun koruyucu etkisi, 20. Ulusal Biyokimya Kongresi-Türk Biyokimya Dergi, 29 Ekim 2008, 162, 2008(Kağa E, Kahraman A, Hünkerler Z., ile birlikte)
0Eserlere Yapılan Atıflar
1Changes in tissue-oxidative stress markers in an experimental model of laparoscopic donor nephrectomy
2Protective effect of erythropoietin on renal ischemia and reperfusion injury
3Changes in serum markers of oxidative stress with varying periods of haemodialysis
4Comparison of the effects of low intra-abdominal pressure and ischaemic preconditioning on the generation of oxidative stress markers and inflammatory cytokines during laparoscopy in rats
5Obstructive sleep apnoea, glucose tolerance and liver steatosis in obese women
6The effect of verapamil on the prevention of ischemia/reperfusion injury in the experimental retroperitoneoscopic donor nephrectomy model
7Effects of melatonin on the oxidant/antioxidant status and lung histopathology in rabbits exposed to cigarette smoke
8Autonomic dysfunction is associated with oxidative stress in non-diabetic hemodialysis patients
9Changes in antioxidant enzyme activities following thrombolytic therapy in acute myocardial infarction
10Oxidative stress markers in hepatitis C infected hemodialysis patients
11Effects of ascorbic acid on oxidative system and transient evoked otoacoustic emissions in rabbits exposed to noise
12The comparison of the oxidative stress effects of different gases and intra-abdominal pressures in an experimental rat model
13Expression of cathepsin D in bladder carcinoma: Correlation with pathological features and serum cystatin C levels
14Mast cell stabilizator and antioxidant effects of epidermal growth factor (EGF) on gastric mucosal injury induced by ethanol in rats
15The effect of different intraabdominal pressures on lipid peroxidation and protein oxidation status during laparoscopic cholecystectomy
16The effect of nitric oxide on ischemia-reperfusion injury in rat liver
17The effect of alpha-tocopherol and pentoxyfilline on ischemia-reperfusion induced liver injury in rats
18Protective effect of quercetin on renal ischemia/reperfusion injury in rats
19Effects of short-term transdermal hormone replacement therapy on glycaemic control, lipid metabolism, C-reactive protein and proteinuria in postmenopausal women with type 2 diabetes or hypertension
20Effect of retroperitoneoscopic donor nephrectomy on tissue oxidative stress markers in rabbit pneumoretroperitoneum model
21Beneficial effects of quercetin on oxidative stress induced by ultraviolet A
22Effect of lung ischemia-reperfusion on oxidative stress parameters of remote tissues
23Can preconditioning reduce laparoscopy-induced tissue injury?
24Cardioprotection with resveratrol pretreatment: improved beneficial effects over standard treatment in rat hearts after global ischemia
25Which is more effective in the prevention of renal ischemia-reperfusion-induced oxidative injury in the early period in mice: interleukin (IL)-10 or anti-IL-12?
26Effect of leptin on renal ischemia-reperfusion damage in rats
27Gastroprotective effect of leptin on gastric mucosal injury induced by ischemia-reperfusion is related to gastric histamine content in rats
28The antioxidative and antihistaminic properties of quercetin in ethanol-induced gastric lesions
29Changes in hepatic TNF-alpha levels, antioxidant status, and oxidation products after renal ischemia/reperfusion injury in mice
30Ischemic preconditioning decreases laparoscopy-induced oxidative stress in small intestine
31A comparison of the oxidative stress response and antioxidant capacity of open and laparoscopic hernia repairs
32Oxidant-antioxidant status and pulmonary function in welding workers
Diğer Bilgiler :